Defense: Bioinformatic Approaches to Admixture and Symbiosis

Speaker Name
Paloma Medina
Speaker Title
PhD Candidate
Speaker Organization
Biomolecular Engineering & Bioinformatics PhD
Start Time
End Time
Location
Zoom - https://ucsc.zoom.us/j/2924188717?pwd=MlBCeVhDRC9ZYjl2S0FMVTlOeENkUT09 - Passcode: 861947

Abstract: As DNA sequencing data becomes more prevalent, population genetics and evolutionary genomics are becoming increasingly more data driven, requiring the development of new tools to work with large datasets. In my doctoral research, I develop bioinformatic tools to study two important contributors to evolution: admixture and symbiosis. In my first chapter, I apply a coalescent theory model to Drosophila melanogaster populations and show evidence for African and European admixture in sub-Saharan populations of this species. In subsequent chapters, I develop a data mining approach to classify bacterial symbiont infections in publicly sequencing databases. Moreover, I investigate bacterial density within a wide range of host species and find evidence for symbiont induced host genome evolution.

Event Type
Advancement/Defense
Advisor
Russell Corbett-Detig
Graduate Program
Biomolecular Engineering & Bioinformatics PhD