Todd M. Lowe
- Professor, Biomolecular Engineering
- Biomolecular Engineering
- 831-459-1511
- Physical Sciences Bldg, Room 320
- Tuesdays 3-4pm, Weds 1:15-2:15 pm (Or by appointment)
- SOE2
- Computational and experimental non-coding RNA research
- Comparative transcriptomics
- RNA gene discovery (gene finders) and probabilistic modeling
- RNA-based gene regulation (antisense small RNAs, RNA-guided modification)
- Transfer RNA research - new functions and modes of regulation
- Role of RNA modification in regulation
- Alternative roles of non-coding RNAs (e.g., tRNA-derived small RNAs, piRNAs)
- Genomics of Archaea
- Evolutionary adaptation to extreme environments
- Small nucleolar RNA research
- Evolution of RNA gene familes
- Bernick, D.L., Dennis, P.P., Hochsmann, M. and Lowe, T.M. (2012) Discovery of Pyrobaculum small RNA families with atypical pseudouridine guide RNA features. RNA, 18, 402-411.
- Chan, P.P., Cozen, A.E. and Lowe, T.M. (2011) Discovery of permuted and recently split transfer RNAs in Archaea. Genome biology, 12, R38.
- Lai, L.B., Chan, P.P., Cozen, A.E., Bernick, D.L., Brown, J.W., Gopalan, V. and Lowe, T.M. (2010) Discovery of a minimal form of RNase P in Pyrobaculum. Proc Natl Acad Sci U S A, 107, 22493-22498.
- Chan, P.P., Holmes, A.D., Smith, A.M., Tran, D. and Lowe, T.M. (2012) The UCSC Archaeal Genome Browser: 2012 update. Nucleic Acids Res, 40, D646-652.
- Cozen, A.E., Weirauch, M.T., Pollard, K.S., Bernick, D.L., Stuart, J.M. and Lowe, T.M. (2009) Transcriptional map of respiratory versatility in the hyperthermophilic crenarchaeon Pyrobaculum aerophilum. J Bacteriol, 191, 782-794.
- B.A in Biology, 1992, Williams College, Williamstown MA
- Ph.D. in Molecular Genetics, 1999, Washington Univ. in St. Louis
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